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Digestive and Liver Disease

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Issue cover

March 2023

Volume 55Supplement 1S1-S76

Abstracts of the 55th A.I.S.F. - Italian Association for the Study of the Liver - Annual Meeting 2023

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Current Issue
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Next Issue29th National Congress of Digestive Disease Italian Federation of Societies of Digestive Diseases – FISMAD Rome, Italy 29 March – 1 April 2023

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Editorial Board

Editorial Board

Published in issue: March 2023

i-ii

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Abstract only

Nationwide survey of liver transplantation for Primary Sclerosing Cholangitis in Italy

M.C. Morelli,
M. Gambato,
S. Martini,
...
S. Marenco,
L. Mameli,
P. Burra

Published in issue: March 2023

S1

PDF

SIRT5 rs12216101 T>G variant is associated with oxidative stress and mitochondrial dysfunction in patients with non-alcoholic fatty liver disease

F. Salomone,
R.M. Pipitone,
M. Longo,
...
L. Valenti,
S. Petta,
S. Grimaudo

Published in issue: March 2023

S2

PDF

Increased level of presepsin in patients with acutely decompensated cirrhosis predicts development of acute-on-chronic liver failure

A. Zanetto,
M.M. Mion,
A. Ferrarese,
...
D. Basso,
P. Burra,
M. Senzolo

Published in issue: March 2023

S2-S3

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Network meta-analysis of first-line systemic therapies for advanced hepatocellular carcinoma: Who is the winner?

C. Celsa,
G. Cabibbo,
G.E.M. Rizzo,
...
S. Battaglia,
M. Vaccaro,
C. Cammà

Published in issue: March 2023

S3

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The invasion of the biliary epithelial cells by CD103⁺ CD69⁺ intraepithelial cells CD8⁺ T lymphocyte and its role in the pathogenesis of primary biliary cholangitis

V. Ronca,
S. Davies,
G. Wootton,
N. Krajewska,
G. Reynolds,
Y. Oo

Published in issue: March 2023

S3-S4

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Prediction of response to obeticholic acid in primary biliary cholangitis: Development and validation of the OCA response score (ORS)

A. De Vincentis,
F. Terracciani,
D. D'Amato,
...
U. Vespasiani-Gentilucci,
M. Carbone
on behalf of the Club Epatologi Ospedalieri (CLEO)/Associazione Italiana Gastroenterologi ed Endoscopisti Digestivi Ospedalieri (AIGO) PBC Study Group, the Sicilian PBC Network, the PBC Project Piemonte-Liguria-Valle D'Aosta and the Italian PBC Registry

Published in issue: March 2023

S4-S5

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Interferon gamma-induced protein 10 levels are associated with insulin resistant components in subjects with non-alcoholic fatty liver disease

M. Guariglia,
C. Rosso,
F. Carli,
...
G.M. Saracco,
A. Gastaldelli,
E. Bugianesi

Published in issue: March 2023

S5

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Detection of hepatocellular carcinoma's microvascular invasion at the preoperative CT scan: Artificial intelligence meets radiomics

S. Famularo,
M. Donadon,
C. Penzo,
...
G.L. Grazi,
D. Bernasconi,
G. Torzilli

Published in issue: March 2023

S6

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Predictors of clinical trajectories in patients admitted for acutely decompensated cirrhosis: An external validation of the PREDICT study

E. Pompili,
M. Baldassarre,
G. Bedogni,
...
F. Palmese,
M. Domenicali,
P. Caraceni

Published in issue: March 2023

S6-S7

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Extension of Bulevirtide monotherapy to 72 weeks in HDV patients with compensated cirrhosis: Efficacy and safety from the italian multicenter study (HEP4Di)

M.P. Anolli,
E. Degasperi,
G. D'Offizi,
...
M. Puoti,
F. Piscaglia,
P. Lampertico

Published in issue: March 2023

S7

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Programmed cell death 1 genetic variant and liver damage in nonalcoholic fatty liver disease

R.M. Pipitone,
F. Malvestiti,
G. Pennisi,
...
S. Romeo,
S. Petta,
S. Grimaudo

Published in issue: March 2023

S7-S8

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Cholangiocarcinoma-on-chip: A 3D liver tumor platform for personalized medicine

M.A. Polidoro,
G. Saladino,
E. Ferrari,
M. Rasponi,
S. Marzorati,
A. Lleo

Published in issue: March 2023

S8

PDF

Incidence and predictors of hepatocellular carcinoma in autoimmune hepatitis: A multicenter international study

F. Colapietro,
P. Maisonneuve,
E. Lytvyak,
...
Y. de Boer,
A. Lleo
on behalf of the International Autoimmune Hepatitis Group

Published in issue: March 2023

S8-S9

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Role of extracellular vesicles in sarcopenia associated to chronic liver diseases

L. Barberi,
C. Porcu,
C. Boccia,
...
L. Ridola,
A. Musarò,
M. Merli

Published in issue: March 2023

S9

PDF

Serum procalcitonin predicts mortality independently of the presence of ACLF in patients with cirrhosis and ascites hospitalized for suspicious infection and treated with empiric antibiotic therapy

M. Bianchini,
C. Celsa,
B. Magro,
...
E. Villa,
C. Cammà,
F. Schepis

Published in issue: March 2023

S10

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Long-term outcomes of patients with chronic HBe-negative infection: Differences and transition between inactive carriers and low viremic carriers

G.E.M. Rizzo,
F. Bronte,
G. Rancatore,
P. Graceffa,
G. Falco,
V. Di Marco

Published in issue: March 2023

S10-S11

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Highlighting sex dimorphism in the molecular mechanisms responsible for sarcopenia in a murine model of liver fibrosis

K. Sayaf,
I. Zanotto,
D. Gabbia,
...
R. Rizzuto,
S. De Martin,
F.P. Russo

Published in issue: March 2023

S11

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PNPLA3, MBOAT7 and TM6SF2 modify mitochondrial dynamics in NAFLD patients: Dissecting the role of cell-free circulating mtDNA and copy number

M. Longo,
E. Paolini,
M. Meroni,
...
M. Moggio,
A.L. Fracanzani,
P. Dongiovanni

Published in issue: March 2023

S11

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Validation of a targeted gene panel sequencing for the diagnosis of hereditary chronic liver diseases

G. Passignani,
L. Ronzoni,
I. Marini,
...
S. Pelusi,
D. Prati,
L. Valenti

Published in issue: March 2023

S11-S12

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Noninvasive assessment of liver disease severity in patients with nonalcoholic fatty liver disease and type 2 diabetes

G. Pennisi,
M. Enea,
V. Falco,
...
F.E. Mózes,
M. Pavlides,
S. Petta

Published in issue: March 2023

S12-S13

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A functional interaction between hepatic estrogen receptor-α and PNPLA3 p.I148M inherited variant drives fatty liver disease susceptibility in women

A. Cherubini,
M. Ostadreza,
O. Jamialahmadi,
...
D. Prati,
S. Romeo,
L. Valenti

Published in issue: March 2023

S13

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A simple characterization of dynamic changes in circulating CD8+PD1+ lymphocytes early predicts response to atezolizumab-bevacizumab in hepatocellular carcinoma

C. Giovannini,
F. Suzzi,
F. Tovoli,
...
M. Iavarone,
F. Piscaglia,
L. Gramantieri

Published in issue: March 2023

S13-S14

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Fatty Acid Synthase expression promotes the malignant features of cholangiocarcinoma cells and predicts shorter survival in patients

G. Lori,
C. Raggi,
B. Piombanti,
...
J. Andersen,
M. Lewinska,
F. Marra

Published in issue: March 2023

S14

PDF

Patient-derived liver organoids as an in vitro model to study new personalized therapies targeting VDAC1 in intrahepatic cholangiocarcinoma

S. De Siervi,
S. Conti Nibali,
S. Mantovani,
...
D. Ronchi,
M.G. Lolicato,
C. Turato

Published in issue: March 2023

S14

PDF

CAR-OLT score predicts cardiac contraindications to liver transplant and 1-year cardiovascular complications after transplant

M. Biolato,
S. Martini,
A. Petti,
...
A. Gasbarrini,
R. Romagnoli,
A. Grieco

Published in issue: March 2023

S15

PDF

Validation of elastography criteria and cACLD Risk Model for diagnosis of compensated Advanced Chronic Liver Disease (cACLD) in NAFLD patients

A. Liguori,
M. Zoncapè,
D. Roccarina,
...
A. Grieco,
L. Miele,
E.A. Tsochatzis

Published in issue: March 2023

S15-S16

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Risk factors for viral reactivation in patients with overt or occult Hepatitis B Virus infection receiving immunosuppressive treatments: A systematic review and meta-analysis with decision curve analysis

G.E.M. Rizzo,
C. Celsa,
M. Enea,
...
V. Calvaruso,
V. Di Marco,
C. Cammà

Published in issue: March 2023

S16

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Lack of substantial improvements in the landscape of alcohol-related hepatocellular carcinoma in the last 15 years: The need to improve cancer prevention and surveillance

N. Reggidori,
L. Bucci,
V. Santi,
...
A. Vitale,
F. Trevisani
for the Italian Liver Cancer (ITA.LI.CA) group

Published in issue: March 2023

S16-S17

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Prospective evaluation of screening strategies for NAFLD in people with type-2 diabetes mellitus in the community

R. Forlano,
T. Stanic,
S. Jayawardana,
...
E. Tsochatzis,
M.R. Thursz,
P. Manousou

Published in issue: March 2023

S17-S18

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Long-term results of ab-initio introduction of everolimus after liver transplantation

D. Pedini,
R. Angelico,
R. Latini,
...
L. Toti,
T.M. Manzia,
G. Tisone

Published in issue: March 2023

S19

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Prevalence of hepatitis delta virus among chronic hbvcarriers at AOU Federico II

V. Cossiga,
A. De Conte,
S. Brusa,
...
M. Guarino,
G. Portella,
F. Morisco

Published in issue: March 2023

S19-S20

PDF

Safety and immunogenicity of booster dose in patients with chronic liver disease

V. Cossiga,
M. Capasso,
I. Loperto,
...
M. Guarino,
G. Portella,
F. Morisco

Published in issue: March 2023

S20

PDF

The role of thyroid hormone signalling in liver carcinogenesis: A proof of knowledge

G. Pontillo,
C. Luongo,
M.C. Giglio,
...
R. Troisi,
D. Salvatore,
F. Morisco

Published in issue: March 2023

S20

PDF

Presence and severity of esophageal varices drives portal hypertension-related complications in compensated advanced nonalcoholic fatty liver disease

G. Pennisi,
M. Enea,
M. Viganò,
...
V. Di Marco,
C. Cammà,
S. Petta

Published in issue: March 2023

S21

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TERT-mutated hepatocellular carcinomas have a higher risk of recurrence after surgical resection. A monocentric prospective study

F. Vasuri,
S. Chillotti,
T. Maloberti,
...
M. Cescon,
D. de Biase,
A. D'Errico

Published in issue: March 2023

S21-S22

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Magnetic Resonance-based fibrosis markers in patients with Non-Alcoholic Fatty Liver Disease: Exploratory data from the Turin cohort

D. D'Amato,
D. Tore,
C. Rosso,
...
G.P. Caviglia,
M. Gatti,
E. Bugianesi

Published in issue: March 2023

S22

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Prognostic value of simple non-invasive tests for the risk stratification of hcc development in patients with cirrhosis due to non-alcoholic fatty liver disease

A. Abdulle,
A. Armandi,
G.P. Caviglia,
...
M. Guariglia,
G.M. Saracco,
E. Bugianesi

Published in issue: March 2023

S23

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Low adherence to Mediterranean Diet is associated to sCD163 levels in patients with MAFLD

N. Perez-Diaz-del-Campo,
C. Rosso,
G.P. Caviglia,
...
M.L. Abate,
G.M. Saracco,
E. Bugianesi

Published in issue: March 2023

S23

PDF

A nutrigenetic precision approach for the management of NAFLD

N. Perez-Diaz-del-Campo,
E. Dileo,
G. Castelnuovo,
...
M.L. Abate,
G.M. Saracco,
E. Bugianesi

Published in issue: March 2023

S23-S24

PDF

Social jetlag and mediterranean diet adherence are associated to liver fibrosis in patients with non-alcoholic fatty liver disease

G. Castelnuovo,
G.P. Caviglia,
C. Rosso,
...
D.G. Ribaldone,
G.M. Saracco,
E. Bugianesi

Published in issue: March 2023

S24

PDF

A new metabolic comorbidity score predicts risk of death among cirrhotic patients on waiting list for liver transplantation

S. Parisse,
A. Martini,
F. Martini,
...
G. Mennini,
M. Rossi,
S. Ginanni Corradini

Published in issue: March 2023

S24

PDF

Primary biliary cholangitis case-finding: Monocentrical study on patients with incidental finding of anti-mitochondrial antibodies

S.S. Sciarrone,
B. Lucchino,
A. Adami,
...
G.M. Bulighin,
N. Scattolo,
M.T. Trevisan

Published in issue: March 2023

S24-S25

PDF

The rs1468615 T>C in ABCB4 confers protection against gallstone disease but not against severe liver disease

F. Tavaglione,
O. Jamialahmadi,
A. De Vincentis,
...
A. Picardi,
S. Romeo,
U. Vespasiani-Gentilucci

Published in issue: March 2023

S25-S26

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Glecaprevir/Pibrentasvir is safe and effective in Italian patients with chronic Hepatitis C aged 75 years or older: A multicenter study

N. Pugliese,
V. Calvaruso,
M. Masarone,
...
F.P. Russo,
V. Di Marco,
A. Aghemo

Published in issue: March 2023

S26

PDF

Liver transplantation for polycystic disease: A cumbersome benign disease

A. Calleri,
B. Lavezzo,
L. Biancone,
R. Romagnoli,
S. Martini

Published in issue: March 2023

S26-S27

PDF

Liver transplantation for portopulmonary hypertension responsive to targeted therapy

A. Calleri,
C. Manuli,
M. Saracco,
...
R. Romagnoli,
A. Ottobrelli,
S. Martini

Published in issue: March 2023

S27

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Medium-term outcome of liver recipients from COVID-19 donors

M. Saracco,
D. Cocchis,
F. Tandoi,
F. Rigo,
R. Romagnoli,
S. Martini

Published in issue: March 2023

S27-S28

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Liver transplant outcome of cirrhotic patients treated with coronary stenting and early discontinuation of dual antiplatelet therapy

M. Saracco,
B. Lavezzo,
F. Tandoi,
...
R. Balagna,
R. Romagnoli,
S. Martini

Published in issue: March 2023

S28

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The enigmatic immunoglobulin G4-related disease: A single-centre experience

M. Stegagnini,
L. Cristoferi,
C. Gallo,
M. Carbone,
P. Invernizzi,
S. Massironi

Published in issue: March 2023

S28-S29

PDF

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