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Digestive and Liver Disease

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Issue cover

February 2012

Volume 44Supplement 1S1-S54

Abstracts of the A.I.S.F. - Italian Association for the Study of the Liver - Annual Meeting 2012

23 February 2012 - 24 February 2012

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Editorial Board

Editorial Board

Published in issue: February 2012

i

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Abstract only

OC-1 PDX-1/Hes-1 interactions determine cholangiocyte proliferative response to injury: the significance for sclerosing cholangitis

M. Marzioni,
S. Saccomanno,
L. Agostinelli,
...
C. Candelaresi,
G. Svegliati Baroni,
A. Benedetti

Published in issue: February 2012

S1

PDF

OC-2 Selective reduction in S100A4 nuclear expression by low-dose paclitaxel halts invasiveness of human cholangiocarcinoma cells through a Rac1-independent, Rho-A/Cdc42-dependent mechanism

L. Sambado,
M. Cadamuro,
C. Spirli,
S. Indraccolo,
M. Strazzabosco,
L. Fabris

Published in issue: February 2012

S1-S2

PDF

OC-3 Transplantation of adipose tissue-mesenchymal stem cells in rats with acetaminophen-induced liver failure: effects on oxidative stress and JNK activation

F. Salamone,
I. Barbagallo,
L. Puzzo,
G. Li Volti

Published in issue: February 2012

S2

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OC-4 Myostatin: a novel modulator of hepatic stellate cell biology

W. Delogu,
A. Caligiuri,
S. Galastri,
M. Pinzani,
F. Marra

Published in issue: February 2012

S2

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OC-5 Systemic administration of a novel human umbilical cord mesenchymal stem cells population accelerates the resolution of acute liver injury

D. Arcidiacono,
D. Bizzaro,
T. Chioato,
...
U. Cillo,
F.P. Russo,
P. Burra

Published in issue: February 2012

S2-S3

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OC-6 Monocyte/macrophage peribiliary recruitment by Pkhd1-defective cholangiocytes induces expression of αvβ6 integrin on biliary cysts via TGFβ1 and TNFα in congenital hepatic fibrosis

L. Locatelli,
C. Spirli,
M. Cadamuro,
...
D. Schuppan,
M. Strazzabosco,
L. Fabris

Published in issue: February 2012

S3

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OC-7 NK profiles of non-responder and relapser patients with cHCV infection treated with SOC

B. Oliviero,
D. Mele,
E. Degasperi,
...
C. Tinelli,
M. Colombo,
M.U. Mondelli

Published in issue: February 2012

S3

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OC-8 IL28B and PNPLA3 polymorphisms affect histological liver damage in patients with non-alcoholic fatty liver disease

S. Petta,
S. Grimaudo,
C. Cammá,
...
G. Licata,
R.M. Pipitone,
A. Craxì

Published in issue: February 2012

S3

PDF

OC-9 IL6, IL6-induced miRNAs and HNF1α/HNF4α in the epigenetic control of cccDNA transcription

C. Scisciani,
N. Pediconi,
J. Lucifora,
...
U. Protzer,
M. Levrero,
L. Belloni

Published in issue: February 2012

S4

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OC-10 IL28B genotype, differential expression of intrahepatic interferon-stimulated genes and response to PEG-IFN and ribavirin therapy in an Italian prospective cohort of genotype 1 hepatitis C patients in “real life”

B. Testoni,
C. Scisciani,
S. Grimaudo,
...
A. Craxì,
M. Levrero
the Multicenter Italian Group for the Study of Hepatitis C

Published in issue: February 2012

S4

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OC-11 IL28B polymorphism in chronic HBV infection: the CC allele does not correlate with the phase of the infection nor with HBsAg clearance in IFN treated patients

B. Cherubini,
P. Colombatto,
B. Coco,
...
A.L. Zignego,
F. Bonino,
M.R. Brunetto

Published in issue: February 2012

S4-S5

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OC-12 Identification of lamivudine resistant HBV strain rt204V/I in acute hepatitis B in Italy

N. Coppola,
G. Tonziello,
P. Colombatto,
...
D. Cavallone,
M.R. Brunetto,
E. Sagnelli

Published in issue: February 2012

S5

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OC-13 The role of VEGF and VEGFR polymorphisms in the prediction of clinical outcome for advanced hepatocellular carcinoma receiving sorafenib

L. Faloppi,
S. De Minicis,
M. Scartozzi,
...
A. Benedetti,
S. Cascinu,
G. Svegliati Baroni

Published in issue: February 2012

S5

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OC-14 Prevalence of occult HBV infection reactivation in a large cohort of Non-Hodgkin Lymphoma (NHL) patients: a retrospective study

M. Masarone,
A. De Renzo,
V. Rosato,
R. Lebano,
S. Tartaglia,
M. Persico

Published in issue: February 2012

S5-S6

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OC-15 Videocapsule endoscopy in patients with portal hypertension: small bowel findings before and following transgiugular intrahepatic portosystemic shunt

I. Pentassuglio,
M. Cesarini,
L. Ridola,
M. Merli,
P. Vernia,
O. Riggio

Published in issue: February 2012

S6

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OC-16 Low efficacy of current nucleic acid testing (NAT) assay for the identification of occult HBV infection (OBI) and consequences for safety of blood supply in Italy

M. Spreafico,
B. Foglieni,
A. Berzuini,
...
I. Guarnori,
A. Colli,
D. Prati

Published in issue: February 2012

S6

PDF

OC-17 The A736V TMPRSS6 polymorphism is associated with the penetrance of hereditary hemochromatosis and hepatocellular carcinoma in C282Y+/+ patients

L. Valenti,
A.L. Fracanzani,
R. Rametta,
...
P. Dongiovanni,
D. Conte,
S. Fargion

Published in issue: February 2012

S6

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OC-18 CD133+ stem cells for the treatment of end stage liver disease

L. Brodosi,
L. Catani,
S. Lorenzini,
...
M. Bernardi,
R.M. Lemoli,
P. Andreone

Published in issue: February 2012

S7

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OC-19 Key role of chymase in the hepatic production of angiotensin II and in the development of experimental liver cirrhosis and its complications

G. Sansoè,
M. Aragno,
R. Mastrocola,
...
A. Smedile,
M. Rizzetto,
M. Parola

Published in issue: February 2012

S7

PDF

OC-20 Role of real-time shear wave elastography in assessing fibrosis in chronic hepatitis C

G. Ferraioli,
C. Tinelli,
B. Dal Bello,
R. Lissandrin,
M. Zicchetti,
C. Filice

Published in issue: February 2012

S7

PDF

OC-21 The diagnostic accuracy of Fibroscan for cirrhosis is influenced by liver morphometry in HCV patients with an SVR

G.M. Prati,
R. D'Ambrosio,
M. Fraquelli,
...
V. Paradis,
P. Bedossa,
M. Colombo

Published in issue: February 2012

S7-S8

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OC-22 Human gallbladder is a highly available source of stem cells with multiple endodermic mature fates potentiality

V. Cardinale,
G. Carpino,
R. Gentile,
...
L. Reid,
E. Gaudio,
D. Alvaro

Published in issue: February 2012

S8

PDF

OC-23 Urinary ethyl glucuronide improves the detection of alcohol consumption in liver transplant candidates and recipients

S. Piano,
S. Cardillo,
L. Marchioro,
...
M. Plebani,
A. Gatta,
P. Angeli

Published in issue: February 2012

S8

PDF

OC-24 Interaction between cyclosporine and recipient IL-28B rs12979860 C>T genetic polymorphisms in the achievement of sustained viral response for recurrent hepatitis C

D. Bitetto,
E. Falleti,
E. Fornasiere,
...
T. De Feo,
C. Fabris,
P. Toniutto

Published in issue: February 2012

S8-S9

PDF

OC-25 The genetic background differentially affects hepatic necro-inflammation in response to CCL2 in a murine model of steatohepatitis

S. Galastri,
E. Zamara,
S. Milani,
...
E. Albano,
M. Parola,
F. Marra

Published in issue: February 2012

S9

PDF

OC-26 The emerging impact of HCC-NAFLD in Italy

S. Bellentani,
A. Brachetti,
E. Dionigi,
...
F. Farinati,
E. Villa
on behalf of the HCC-NASH Italian Group

Published in issue: February 2012

S9

PDF

OC-27 Hepatic resection versus laparoscopic radiofrequency ablation for “very early” hepatocellular carcinoma

R. Santambrogio,
M. Kluger,
M. Costa,
...
S. Bruno,
E. Opocher,
D. Cherqui

Published in issue: February 2012

S9-S10

PDF

OC-28 Behind D-MELD: the role of primary indication (HCV or HBV) as significant covariate in the outcome prediction after liver transplants

A. Avolio,
S. Agnes,
M. Lirosi,
...
A. Gasbarrini,
U. Cillo
for the Donor-to-Recipient Italian Liver Transplant (DR2-ILTx) Study Group

Published in issue: February 2012

S10

PDF

OC-29 Terlipressin and albumin vs midodrine plus octreotide and albumin in the treatment of hepatorenal syndrome in patients with cirrhosis: results of a controlled clinical trial by A.I.S.F.

M. Cavallin,
M. Merli,
S. Fasolato,
...
P. Caraceni,
A. Gatta,
P. Angeli

Published in issue: February 2012

S10

PDF

OC-30 Interleukin-28B (IL-28B) polymorphism has no impact on the long-term outcome of patients with HCV-related cirrhosis: a 15-years retrospective-prospective cohort study

S. Bruno,
C. Facciotto,
A. Crosignani,
...
A. Camera,
P. Maisonneuve,
E. Villa

Published in issue: February 2012

S10-S11

PDF

OC-31 Low rates of SVR to peg-interferon plus ribavirin in HCV genotype 1 IL28B rs12979860 CC cirrhotic patients without rapid virological response

E. Degasperi,
A. Aghemo,
E. Galmozzi,
...
R. Soffredini,
M.G. Rumi,
M. Colombo

Published in issue: February 2012

S11

PDF

OC-32 Costs and quality of life in patients with chronic hepatic diseases: the COME study results

S. Fagiuoli,
L. Scalone,
R. Ciampichini,
...
A. Del Prete,
I. Gardini,
L.G. Mantovani

Published in issue: February 2012

S11

PDF

OC-33 Non-invasive diagnosis of non-alcoholic steatohepatitis by combined cytokeratin-18 apoptotic fragment and elastometry

S. Carenzi,
C. Rosso,
L. Mezzabotta,
...
A. Smedile,
M.L. Abate,
E. Bugianesi

Published in issue: February 2012

S11-S12

PDF

OC-34 Clinical features and outcome of patients with drug-induced autoimmune hepatitis

A. Licata,
G. Butera,
F.S. Macaluso,
D. Cabibi,
A. Craxì,
P.L. Almasio

Published in issue: February 2012

S12

PDF

OC-35 PEG-IFN for chronic hepatitis C in clinical practice: the prospective phase of the AIFA study

F. Rosina,
M.E. Tosti,
E. Borghesio,
...
F. Pallone,
G. Carosi,
M. Rizzetto

Published in issue: February 2012

S12

PDF

OC-36 Peripheral insulin resistance rather than hepatic is a primary defect in non obese, non diabetic, non dyslipidemic NAFLD patients: correlation with liver damage

L. Mezzabotta,
E. Bugianesi,
F. Salamone,
...
R. Gambino,
M. Cassader,
A. Gastaldelli

Published in issue: February 2012

S12-S13

PDF

T-1 Inhibition of chymase-dependent production of kidney angiotensin II improves renal sodium handling and prevents ascites in experimental liver cirrhosis

G. Sansoè,
M. Aragno,
R. Mastrocola,
...
A. Smedile,
M. Parola,
M. Rizzetto

Published in issue: February 2012

S14

PDF

T-2 A morphometric and immunohistochemical study to assess the benefit of an SVR in HCV cirrhotic patients

R. D' Ambrosio,
A. Aghemo,
M.G. Rumi,
...
V. Paradis,
M. Colombo,
P. Bedossa

Published in issue: February 2012

S14

PDF

T-3 Ramp-up strategy and long-term results of sorafenib in advanced-stage hepatocellular carcinoma under daily clinical practice conditions

R. Sacco,
I. Bargellini,
B. Ginanni,
...
A. Scaramuzzino,
G. Bresci,
C. Bartolozzi

Published in issue: February 2012

S14

PDF

T-4 Thyroid-stimulating hormone serum level, liver thyroid-stimulating hormone-receptor, and severe fibrosis in genotype 1 chronic hepatitis C patients with normal thyroid function

S. Petta,
A. Mazzola,
S. Grimaudo,
...
G.C. Morreale,
R.M. Pipitone,
A. Craxì

Published in issue: February 2012

S15

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T-5 High sCD36 plasma level is associated with steatosis and its severity in patients with chronic genotype 1 hepatitis C

S. Petta,
A. Handberg,
G. Marchesini,
...
D. Cabibi,
F.S. Macaluso,
A. Craxì

Published in issue: February 2012

S15

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T-6 Hyperuricemia is associated with severe steatosis in patients with chronic hepatitis C

S. Petta,
F.S. Macaluso,
D. Cabibi,
C. Cammà,
V. Di Marco,
A. Craxì

Published in issue: February 2012

S15

PDF

T-7 The course of bone mineral density in patients with chronic hepatitis B long term treated with nucleos(t)ide analogs: a longitudinal cohort study

M. Viganò,
P. Lampertico,
R. Soffredini,
...
F. Facchetti,
P. Beck-Peccoz,
M. Colombo

Published in issue: February 2012

S15-S16

PDF

T-8 Entecavir monotherapy in 418 NUC-naive patients with chronic hepatitis B from field practice: high efficacy and favorable safety profile over 3 years of treatment

P. Lampertico,
M. Viganò,
R. Soffredini,
...
M. Quagliuolo,
G. Lunghi,
M. Colombo

Published in issue: February 2012

S16

PDF

T-9 2-year effectiveness and safety of tenofovir in 302 NUC-naive patients with chronic hepatitis B: a multicenter European study in clinical practice

P. Lampertico,
R. Soffredini,
M. Viganò,
...
F. Facchetti,
F. Invernizzi,
M. Colombo

Published in issue: February 2012

S16-S17

PDF

T-10 MiR-221/Mdm2/p53 control loop sensitizes hepatocellular carcinoma cells to anti-cancer treatments

F. Fornari,
M. Milazzo,
C. Giovannini,
...
M. Negrini,
L. Gramantieri,
L. Bolondi

Published in issue: February 2012

S17

PDF

T-11 Early assessment of response to sorafenib in advanced hepatocellular carcinoma using perfusional computed tomography: pilot study

R. Sacco,
I. Bargellini,
B. Ginanni,
...
A. Scaramuzzino,
G. Bresci,
C. Bartolozzi

Published in issue: February 2012

S17

PDF

T-12 Rods and rings autoantibodies developing in chronic hepatitis C patients treated with peginterferon and ribavirin target inosine-5’-monophosphate dehydrogenase 2 (IMPDH2)

G. Covini,
E. Bredi,
W.C. Carcamo,
...
M.G. Pich,
M. Colombo,
E.K.L. Chan

Published in issue: February 2012

S17-S18

PDF

T-13 A new panoramic 3-dimensional US (3D NAV CEUS) for HCC detection during follow up in cirrhotic patients

F. Giangregorio,
L. Quinto,
L. Fanigliulo,
...
G. Sbolli,
M. Di Stasi,
F. Fornari

Published in issue: February 2012

S18

PDF

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