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Digestive and Liver Disease
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    • Cover Image - Digestive and Liver Disease, Volume 55, Issue 3
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  • Alimentary Tract

    Six year adalimumab efficacy in steroid-dependent Crohn's disease patients: A prospective single-center real life study

    Digestive and Liver Disease
    Vol. 48Issue 11p1314–1317Published online: August 28, 2016
    • Ambrogio Orlando
    • Sara Renna
    • Filippo Mocciaro
    • Maria Cappello
    • Marco Giunta
    • Marco Mendolaro
    • and others
    Cited in Scopus: 4
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      Adalimumab is effective in the treatment of Crohn's disease. We have already reported data on the efficacy of adalimumab in 110 steroid-dependent patients. At the end of the study 90 patients (64.5%) maintained clinical remission.
      Six year adalimumab efficacy in steroid-dependent Crohn's disease patients: A prospective single-center real life study
    • Review Article

      Evolving roles of cross-sectional imaging in Crohn's disease

      Digestive and Liver Disease
      Vol. 48Issue 9p975–983Published online: June 20, 2016
      • Andrea Magarotto
      • Stefania Orlando
      • Marina Coletta
      • Dario Conte
      • Mirella Fraquelli
      • Flavio Caprioli
      Cited in Scopus: 9
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        The implementation of cross-sectional imaging techniques for the clinical management of Crohn's disease patients has steadily grown over the recent years, thanks to a series of technological advances, including the evolution of contrast media for magnetic resonance, computed tomography and bowel ultrasound. This has resulted in a continuous improvement of diagnostic accuracy and capability to detect Crohn's disease-related complications. Additionally, a progressive widening of indications for cross-sectional imaging in Crohn's disease has been put forward, thus leading to hypothesize that in the near future imaging techniques can increasingly complement endoscopy in most clinical settings, including the grading of disease activity and the assessment of mucosal healing or Crohn's disease post-surgical recurrence.
        Evolving roles of cross-sectional imaging in Crohn's disease
      • Position Paper

        French national consensus clinical guidelines for the management of ulcerative colitis

        Digestive and Liver Disease
        Vol. 48Issue 7p726–733Published online: May 3, 2016
        • Laurent Peyrin-Biroulet
        • Yoram Bouhnik
        • Xavier Roblin
        • Guillaume Bonnaud
        • Hervé Hagège
        • Xavier Hébuterne
        • and others
        Cited in Scopus: 14
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          Ulcerative colitis (UC) is a chronic inflammatory bowel disease of multifactorial etiology that primarily affects the colonic mucosa. The disease progresses over time, and clinical management guidelines should reflect its dynamic nature. There is limited evidence supporting UC management in specific clinical situations, thus precluding an evidence-based approach.
          French national consensus clinical guidelines for the management of ulcerative colitis
        • Alimentary Tract

          Burden of disease and patient-reported outcomes in patients with moderate to severe ulcerative colitis in the last 12 months – Multicenter European cohort study

          Digestive and Liver Disease
          Vol. 48Issue 6p592–600Published online: February 26, 2016
          • Gert Van Assche
          • Laurent Peyrin-Biroulet
          • Andreas Sturm
          • Javier P. Gisbert
          • Daniel R. Gaya
          • Bern Bokemeyer
          • and others
          Cited in Scopus: 30
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            Treatment of ulcerative colitis (UC) is aimed at maintaining corticosteroid-free remission and improving quality of life (QoL).
            Burden of disease and patient-reported outcomes in patients with moderate to severe ulcerative colitis in the last 12 months – Multicenter European cohort study
          • Alimentary Tract

            Short term colectomy rate and mortality for severe ulcerative colitis in the last 40 years. Has something changed?

            Digestive and Liver Disease
            Vol. 48Issue 4p371–375Published online: February 4, 2016
            • Valeria Clemente
            • Annalisa Aratari
            • Claudio Papi
            • Piero Vernia
            Cited in Scopus: 14
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              About 20% of ulcerative colitis patients will experience a severe attack during the course of the disease. Intensive treatment, early surgery and, more recently, “rescue therapies” improved prognosis.
              Short term colectomy rate and mortality for severe ulcerative colitis in the last 40 years. Has something changed?
            • Alimentary Tract

              The burden of anaemia in patients with inflammatory bowel diseases

              Digestive and Liver Disease
              Vol. 48Issue 3p267–270Published online: December 14, 2015
              • Anna Testa
              • Antonio Rispo
              • Marco Romano
              • Gabriele Riegler
              • Francesco Selvaggi
              • Erminia Bottiglieri
              • and others
              Cited in Scopus: 16
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                Anaemia (AN) is frequently associated with inflammatory bowel diseases (IBD) and can negatively influence the quality of life of patients.
                The burden of anaemia in patients with inflammatory bowel diseases
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