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Special Article
Open Access
Primary Biliary Cholangitis: advances in management and treatment of the disease
Digestive and Liver Disease
Vol. 49Issue 8p841–846Published online: May 8, 2017
- Pietro Invernizzi
- Annarosa Floreani
- Marco Carbone
- Marco Marzioni
- Antonio Craxi
- Luigi Muratori
- and others
Cited in Scopus: 20
Primary Biliary Cholangitis, previously known as Primary Biliary Cirrhosis, is a rare disease, which mainly affects women in their fifth to seventh decades of life. It is a chronic autoimmune disease characterized by a progressive damage of interlobular bile ducts leading to ductopenia, chronic cholestasis and bile acids retention. Even if the disease usually presents a long asymptomatic phase and a slow progression, in many patients it may progress faster toward cirrhosis and its complications.