Abstract
Background and aim
Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) for the treatment of gastric
outlet obstruction (GOO) has been actually performed only with one type of electrocautery
lumen-apposing metal stents (EC-LAMS). We aimed to evaluate the safety, technical
and clinical effectiveness of EUS-GE using a newly available EC-LAMS in patients with
malignant and benign GOO.
Materials and methods
Consecutive patients who underwent EUS-GE for GOO using the new EC-LAMS at five endoscopic
referral centers were retrospectively evaluated. Clinical efficacy was determined
utilizing the Gastric Outlet Obstruction Scoring System (GOOSS).
Results
Twenty-five patients (64% male, mean age 68.7 ± 9.3 years) met the inclusion criteria;
21 (84%) had malignant etiology. Technically, EUS-GE was successful in all patients,
with a mean procedural time of 35 ± 5 min. Clinical success was 68% at 7 days and
100% at 30 days. The mean time to resume oral diet was 11.4 ± 5.8 h, with an improvement
of at least one point of GOOSS score observed in all patients. The median hospital
stay was 4 days. No procedure-related adverse events occurred. After a mean follow-up
of 7.6 months (95% CI 4.6–9.2), no stent dysfunctions were observed.
Conclusion
This study suggests EUS-GE can be performed safely and successfully using the new
EC-LAMS. Future large multicenter prospective studies are needed to confirm our preliminary
data.
Keywords
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Article info
Publication history
Published online: March 06, 2023
Accepted:
February 14,
2023
Received:
November 9,
2022
Publication stage
In Press Corrected ProofFootnotes
Ethical approval to conduct this study was obtained on 07/19/2022 (protocol number n. 38/22 HMD).
Identification
Copyright
© 2023 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
