Cirrhosis is a frequent cause for hospitalization, with up to 15% in the United Kingdom
and 25,000 patients in the United States requiring Intensive Care Unit (ICU) care
[
[1]
,
[2]
]. Patients with cirrhosis requiring ICU care are at risk for high inpatient mortality
and represent an economic burden, with a total of $9.8 billion in expenses for direct
patient care in 2011 [
[3]
,
[4]
]. Alcohol-associated cirrhosis (ALC) worldwide accounts for over 330,000 deaths,
which represented 27.3% of all cirrhosis-related deaths in 2017 [
[5]
]. Several scores, such as Child-Pugh, MELD, MELD-Na, ABC-lactate, and CLIF-SOFA, have
been developed to estimate disease severity and prognosis for hospitalized patients
with cirrhosis, however these are limited by sample size, lack of validation, and
inaccuracy [
[6]
].To read this article in full you will need to make a payment
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References
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- Increasing Burden of Acute-On-Chronic Liver Failure Among Alcohol-Associated Liver Disease in the Young Population in the United States.Am J Gastroenterol. 2020; 115: 88-95
- The MELD Score Is Superior to the Maddrey Discriminant Function Score to Predict Short-Term Mortality in Alcohol-Associated Hepatitis: a Global Study.Am J Gastroenterol. 2022; 117: 301-310
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Article info
Publication history
Published online: February 13, 2023
Accepted:
January 30,
2023
Received:
January 24,
2023
Publication stage
In Press Corrected ProofFootnotes
Conflicts of interest: None
Financial Disclosures: None
Identification
Copyright
© 2023 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
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