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Effectiveness of double-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography (DBE-ERCP): A multicenter real-world study

Published:November 12, 2022DOI:https://doi.org/10.1016/j.dld.2022.10.014

      Abstract

      Background and aims

      To investigate the effectiveness of double-balloon enteroscope-assisted retrograde cholangiopancreatography (DBE-ERCP) in patients with gastrointestinal surgically altered anatomy (SAA).

      Methods

      From May 2013 to October 2021, all consecutive patients undergoing DBE-ERCP in three gastroenterological referral centers in Northern Italy were enrolled in the study. Patients were assessed regarding their medical history, previous surgery, time from previous surgery to the DBE-ERCP procedure, and the success or failure of DBE-ERCP.

      Results

      Fifty-three patients (60% men, median age 65 (23–89) years) undergoing 67 DBE-ERCP procedures (1–3 DBE-ERCP per patient) were enrolled. Reasons for SAA included orthotopic liver transplantation (23%), ulcers (15%), malignancies (43%), difficult cholecystectomy (17%), and other causes (2%). Types of surgery included Roux-en-Y biliodigestive anastomosis (45%), Roux-en-Y gastrectomy (32%), pancreaticoduodenectomy (17%), and Billroth II gastrectomy (6%). The overall DBE-ERCP success rate was 86%. The type of surgery, indications, and the length of time between previous surgery and DBE-ERCP were not statistically associated with DBE-ERCP success. The DBE-ERCP success rate increased from 2018 to 2021.

      Conclusions

      DBE-ERCP is a successful procedure in challenging patients with SAA. The improvement in results over time indicates the necessity of adequate training and of centralizing patients in referral centers.

      Keywords

      Abbreviations:

      B2 (Billroth II), DBE (double-balloon endoscopy), ERCP (endoscopic retrograde cholangiopancreatography), OLT (orthotopic liver transplantation), PD (pancreatoduodenectomy), RY (Roux-en-Y), RYGB (Roux-en-Y gastric bypass), RYHJ (Roux-en-Y hepaticojejunostomy), PTBD (percutaneous transhepatic biliary drainage)
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