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Pregnancy-related complications in autoimmune atrophic gastritis: A monocentric experience

Published:October 23, 2022DOI:https://doi.org/10.1016/j.dld.2022.10.003
      Autoimmune atrophic gastritis (AAG) is an organ-specific disease which causes atrophy of the gastric oxyntic mucosa [
      • Lenti M.V.
      • Rugge M.
      • Lahner E.
      • Miceli E.
      • Toh B.H.
      • Genta R.M.
      • et al.
      Autoimmune gastritis.
      ]. AAG has subtle clinical manifestations, responsible for substantial diagnostic delay [
      • Lenti M.V.
      • Rugge M.
      • Lahner E.
      • Miceli E.
      • Toh B.H.
      • Genta R.M.
      • et al.
      Autoimmune gastritis.
      ]. As AAG often clusters with other autoimmune diseases [
      • Lenti M.V.
      • Miceli E.
      • Cococcia S.
      • Klersy C.
      • Staiani M.
      • Guglielmi F.
      • et al.
      Determinants of diagnostic delay in autoimmune atrophic gastritis.
      ] and predisposes to the development of type I gastric neuroendocrine tumours and gastric adenocarcinoma [
      • Lenti M.V.
      • Rugge M.
      • Lahner E.
      • Miceli E.
      • Toh B.H.
      • Genta R.M.
      • et al.
      Autoimmune gastritis.
      ], it should be promptly diagnosed. The most common AAG-related manifestations are due to vitamin B12 deficiency [
      • Lenti M.V.
      • Rugge M.
      • Lahner E.
      • Miceli E.
      • Toh B.H.
      • Genta R.M.
      • et al.
      Autoimmune gastritis.
      ]. Clinical manifestations may revert after supplementation [
      • Miceli E.
      • Lenti M.V.
      • Padula D.
      • Luinetti O.
      • Vattiato C.
      • Monti C.M.
      • et al.
      Common features of patients with autoimmune atrophic gastritis.
      ].

      Keywords

      Abbreviations:

      AAG (autoimmune atrophic gastritis)
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