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Correspondence| Volume 55, ISSUE 1, P146-148, January 2023

Pregnancy-related complications in autoimmune atrophic gastritis: A monocentric experience

Published:October 23, 2022DOI:https://doi.org/10.1016/j.dld.2022.10.003
Pregnancy-related complications in autoimmune atrophic gastritis: A monocentric experience
Previous ArticleDirect portal pressure gradient measurement in patients with porto-sinusoidal vascular disease
      Autoimmune atrophic gastritis (AAG) is an organ-specific disease which causes atrophy of the gastric oxyntic mucosa [
      • Lenti M.V.
      • Rugge M.
      • Lahner E.
      • Miceli E.
      • Toh B.H.
      • Genta R.M.
      • et al.
      Autoimmune gastritis.
      Nat Rev Dis Primer. 2020; 9: 56
      ]. AAG has subtle clinical manifestations, responsible for substantial diagnostic delay [
      • Lenti M.V.
      • Rugge M.
      • Lahner E.
      • Miceli E.
      • Toh B.H.
      • Genta R.M.
      • et al.
      Autoimmune gastritis.
      Nat Rev Dis Primer. 2020; 9: 56
      ]. As AAG often clusters with other autoimmune diseases [
      • Lenti M.V.
      • Miceli E.
      • Cococcia S.
      • Klersy C.
      • Staiani M.
      • Guglielmi F.
      • et al.
      Determinants of diagnostic delay in autoimmune atrophic gastritis.
      Aliment Pharmacol Ther. 2019; 50: 167-175
      ] and predisposes to the development of type I gastric neuroendocrine tumours and gastric adenocarcinoma [
      • Lenti M.V.
      • Rugge M.
      • Lahner E.
      • Miceli E.
      • Toh B.H.
      • Genta R.M.
      • et al.
      Autoimmune gastritis.
      Nat Rev Dis Primer. 2020; 9: 56
      ], it should be promptly diagnosed. The most common AAG-related manifestations are due to vitamin B12 deficiency [
      • Lenti M.V.
      • Rugge M.
      • Lahner E.
      • Miceli E.
      • Toh B.H.
      • Genta R.M.
      • et al.
      Autoimmune gastritis.
      Nat Rev Dis Primer. 2020; 9: 56
      ]. Clinical manifestations may revert after supplementation [
      • Miceli E.
      • Lenti M.V.
      • Padula D.
      • Luinetti O.
      • Vattiato C.
      • Monti C.M.
      • et al.
      Common features of patients with autoimmune atrophic gastritis.
      Clin Gastroenterol Hepatol. 2012; 10: 812-814
      ].

      Keywords

      Abbreviations:

      AAG (autoimmune atrophic gastritis)
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      References

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        Determinants of diagnostic delay in autoimmune atrophic gastritis.
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      Article info

      Publication history

      Published online: October 23, 2022
      Accepted: October 5, 2022
      Received: July 29, 2022

      Footnotes

      ✰Guarantor of the article: Marco Vincenzo Lenti

      Identification

      DOI: https://doi.org/10.1016/j.dld.2022.10.003

      Copyright

      © 2022 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

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