Abstract
Background
This study evaluated the prevalence of cardiovascular risk-factors in patients with
mesenteric panniculitis.
Aims
To determine whether cardiovascular risk-factors and mesenteric panniculitis are associated.
Methods
Retrospective, matched case-control study of patients referred to Meir Medical Center,
Israel, 2014–2019, who underwent computerized tomography scan, were diagnosed mesenteric
panniculitis by radiologic criteria. They were compared to two, matched case-control
groups: hospitalized patients without mesenteric panniculitis and the general population
based on Israeli Ministry of Health surveys. Patients with active malignancy, IBD
or significant intra-abdominal morbidity were excluded.
Results
Of 376 patients with mesenteric panniculitis diagnosed by computerized tomography,
187 were included. Compared to hospital patients, they had higher incidence of dyslipidemia
(77.5%/56.7%), hypertension (52.4%/40.6%), obesity (body mass index>30) (60.4%/30.5%)
and nonalcoholic fatty liver disease (42.2%/16.6%). Similar differences were observed
compared to the general population. In multivariable logistic regression, dyslipidemia,
obesity, and nonalcoholic fatty liver disease were independent predictors for mesenteric
panniculitis.
Conclusions
Patients with mesenteric panniculitis have more cardiovascular risk-factors compared
to a case-control group and to the general population. This suggests that mesenteric
panniculitis is clinically significant and may be part of the metabolic morbidity
burden. This association should be further explored.
Keywords
Abbreviations:
NAFLD (nonalcoholic fatty liver disease), MP (Mesenteric panniculitis)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: July 16, 2022
Accepted:
June 19,
2022
Received:
April 28,
2022
Identification
Copyright
© 2022 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
