Advertisement

Clustering Reveals the Prognostic Role of Serum Albumin Values Within the Normal Range in Patients with Primary Biliary Cholangitis

  • Author Footnotes
    ⁎ These authors share first authorship.
    A. Gerussi
    Footnotes
    ⁎ These authors share first authorship.
    Affiliations
    Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy

    European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy
    Search for articles by this author
  • Author Footnotes
    ⁎ These authors share first authorship.
    D. Verda
    Footnotes
    ⁎ These authors share first authorship.
    Affiliations
    Rulex Inc., Newton, MA, USA – www.rulex.ai
    Search for articles by this author
  • D.P. Bernasconi
    Affiliations
    Bicocca Bioinformatics Biostatistics and Bioimaging Centre - B4, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
    Search for articles by this author
  • M. Carbone
    Affiliations
    Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy

    European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy
    Search for articles by this author
  • A. Komori
    Affiliations
    Clinical Research Center, National Hospital Organization (NHO) Nagasaki Medical Center, Nagasaki, Japan
    Search for articles by this author
  • M. Abe
    Affiliations
    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan
    Search for articles by this author
  • M. Inao
    Affiliations
    Department of Gastroenterology and Hepatology, Faculty of Medicine, Saitama Medical University, Saitama, Japan
    Search for articles by this author
  • T. Namisaki
    Affiliations
    Department of Gastroenterology, Nara Medical University, Nara, Japan
    Search for articles by this author
  • S. Mochida
    Affiliations
    Department of Gastroenterology and Hepatology, Faculty of Medicine, Saitama Medical University, Saitama, Japan
    Search for articles by this author
  • H. Yoshiji
    Affiliations
    Department of Gastroenterology, Nara Medical University, Nara, Japan
    Search for articles by this author
  • G. Hirschfield
    Affiliations
    Toronto Centre for Liver Disease, Toronto Western & General Hospital, University Health Network , Toronto, Canada

    Institute of Medical Science, University of Toronto, Toronto, Canada
    Search for articles by this author
  • K. Lindor
    Affiliations
    Division of Gastroenterology and Hepatology, Mayo Clinic, Phoenix, Arizona, United States

    Arizona State University, Phoenix, Arizona, United States
    Search for articles by this author
  • A. Pares
    Affiliations
    Liver Unit, Hospital Clinic, CIBERehd, IDIBAPS, University of Barcelona, Barcelona, Spain

    European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hospital Clinic de Barcelona, Barcelona, Spain
    Search for articles by this author
  • C. Corpechot
    Affiliations
    Centre de Reference des Maladies Inflammatoires des Voies Biliaires, Hôpital Saint- Antoine, Paris, France

    European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Hôpital Saint-Antoine, Paris, France
    Search for articles by this author
  • N. Cazzagon
    Affiliations
    Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy

    European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Azienda Ospedale - Università Padova, Padova, Italy
    Search for articles by this author
  • A. Floreani
    Affiliations
    Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy

    European Reference Network on Hepatological Diseases (ERN RARE-LIVER), Azienda Ospedale - Università Padova, Padova, Italy
    Search for articles by this author
  • M. Marzioni
    Affiliations
    Division of Gastroenterology and Hepatology, Ospedali Riuniti University Hospital, Ancona, Italy
    Search for articles by this author
  • D. Alvaro
    Affiliations
    Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
    Search for articles by this author
  • U. Vespasiani-Gentilucci
    Affiliations
    Clinical Medicine and Hepatology Unit, Campus Bio-Medico University of Rome, Rome, Italy
    Search for articles by this author
  • L. Cristoferi
    Affiliations
    Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy

    European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy

    Bicocca Bioinformatics Biostatistics and Bioimaging Centre - B4, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
    Search for articles by this author
  • M.G. Valsecchi
    Affiliations
    Bicocca Bioinformatics Biostatistics and Bioimaging Centre - B4, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
    Search for articles by this author
  • M. Muselli
    Affiliations
    Rulex Inc., Newton, MA, USA – www.rulex.ai

    Institute of Electronics, Computer and Telecommunication Engineering, National Research Council of Italy, Genova, Italy
    Search for articles by this author
  • the Japan PBC Study Group
    Affiliations
    Rulex Inc., Newton, MA, USA – www.rulex.ai

    Institute of Electronics, Computer and Telecommunication Engineering, National Research Council of Italy, Genova, Italy
    Search for articles by this author
  • the Global PBC Study Group
    Affiliations
    Rulex Inc., Newton, MA, USA – www.rulex.ai

    Institute of Electronics, Computer and Telecommunication Engineering, National Research Council of Italy, Genova, Italy
    Search for articles by this author
  • the Italian PBC study Group
    Affiliations
    Rulex Inc., Newton, MA, USA – www.rulex.ai

    Institute of Electronics, Computer and Telecommunication Engineering, National Research Council of Italy, Genova, Italy
    Search for articles by this author
  • the Japan PBC Study Group
  • the Global PBC Study Group
  • the Italian PBC study group
  • Author Footnotes
    ⁎⁎ These authors share last authorship.
    B.E. Hansen
    Footnotes
    ⁎⁎ These authors share last authorship.
    Affiliations
    Clinical Research Center, National Hospital Organization (NHO) Nagasaki Medical Center, Nagasaki, Japan

    Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan
    Search for articles by this author
  • Author Footnotes
    ⁎⁎ These authors share last authorship.
    A. Tanaka
    Footnotes
    ⁎⁎ These authors share last authorship.
    Affiliations
    Department of Medicine, Teikyo University School of Medicine, Japan
    Search for articles by this author
  • Author Footnotes
    ⁎⁎ These authors share last authorship.
    P. Invernizzi
    Footnotes
    ⁎⁎ These authors share last authorship.
    Affiliations
    Division of Gastroenterology, Centre for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy

    European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy
    Search for articles by this author
  • Author Footnotes
    ⁎ These authors share first authorship.
    ⁎⁎ These authors share last authorship.
      Introduction and Aim: Machine Learning (ML) is revolutionizing medicine, with clustering as one of the most promising ML approaches for prognostication. We explored whether clustering may be helpful in risk stratification in primary biliary cholangitis (PBC).
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Digestive and Liver Disease
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect