Abstract
Background
Colonoscopy demands a considerable amount of resources, and little is known about
its diagnostic yield among inpatients.
Aims
To assess indications, diagnostic yield and findings of colonoscopy for inpatients,
and to identify risk factors for relevant findings and cancer.
Methods
Multicentre, prospective, observational study including 12 hospitals. Consecutive
adult inpatients undergoing colonoscopy were evaluated from February through November
2019.
Results
1,302 inpatients underwent colonoscopy. Diagnostic yield for relevant findings and
cancer was 586 (45%) and 112 (8.6%), respectively. Adequate colon cleansing was achieved
in 896 (68.8%) patients. Split-dose/same-day regimen was adopted in 847 (65%) patients.
Factors associated to relevant findings were age ≥70 years (RR 1.32), male gender
(RR 1.11), blood loss (RR 1.22) and adequate cleansing (RR 1.63). Age ≥70 years (RR
2.08), no previous colonoscopy (RR 2.69) and split-dose/same-day regimen (RR 1.59)
significantly increased cancer detection. Implementing adequate cleansing and split-dose/same-day
regimen in all patients would increase the diagnostic yield for any relevant findings
and cancer from 43% to 70% and from 6% to 10%, respectively.
Conclusion
Relevant colorectal diseases and cancer were frequent among inpatients. Factors associated
with detection of relevant findings were identified. Adequate colon cleansing and
split-dose/same-day regimen significantly increased colonoscopy diagnostic yield.
Keywords
Abbreviations:
BBPS (Boston Bowel Preparation Scale), CI (confidence interval), CRC (colorectal cancer), IQR (interquartile range), NNS (number needed to scope), RR (relative risk), SD (standard deviation), STROBE (Strengthening the Reporting of Observational Studies in Epidemiology)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: November 10, 2020
Accepted:
October 21,
2020
Received:
July 20,
2020
Identification
Copyright
© 2020 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.