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Digestive Endoscopy| Volume 53, ISSUE 2, P224-230, February 2021

The diagnostic yield of colonoscopy in hospitalized patients. An observational multicenter prospective study.

Published:November 10, 2020DOI:https://doi.org/10.1016/j.dld.2020.10.029

      Abstract

      Background

      Colonoscopy demands a considerable amount of resources, and little is known about its diagnostic yield among inpatients.

      Aims

      To assess indications, diagnostic yield and findings of colonoscopy for inpatients, and to identify risk factors for relevant findings and cancer.

      Methods

      Multicentre, prospective, observational study including 12 hospitals. Consecutive adult inpatients undergoing colonoscopy were evaluated from February through November 2019.

      Results

      1,302 inpatients underwent colonoscopy. Diagnostic yield for relevant findings and cancer was 586 (45%) and 112 (8.6%), respectively. Adequate colon cleansing was achieved in 896 (68.8%) patients. Split-dose/same-day regimen was adopted in 847 (65%) patients. Factors associated to relevant findings were age ≥70 years (RR 1.32), male gender (RR 1.11), blood loss (RR 1.22) and adequate cleansing (RR 1.63). Age ≥70 years (RR 2.08), no previous colonoscopy (RR 2.69) and split-dose/same-day regimen (RR 1.59) significantly increased cancer detection. Implementing adequate cleansing and split-dose/same-day regimen in all patients would increase the diagnostic yield for any relevant findings and cancer from 43% to 70% and from 6% to 10%, respectively.

      Conclusion

      Relevant colorectal diseases and cancer were frequent among inpatients. Factors associated with detection of relevant findings were identified. Adequate colon cleansing and split-dose/same-day regimen significantly increased colonoscopy diagnostic yield.

      Keywords

      Abbreviations:

      BBPS (Boston Bowel Preparation Scale), CI (confidence interval), CRC (colorectal cancer), IQR (interquartile range), NNS (number needed to scope), RR (relative risk), SD (standard deviation), STROBE (Strengthening the Reporting of Observational Studies in Epidemiology)
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