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A 59-year-old man presented with complaints of nodular skin lesions for 10 months,
associated with significant weight loss and recurrent episodes of melena for 3 months.
Physical examination revealed multiple cutaneous nodular lesions (Fig. 1) which were firm to hard in consistency. Esophagogastroduodenoscopy revealed multiple
variable sized black colored ulcero-nodular lesions in the fundus, body and antrum
of stomach (arrows) (Fig. 2A). Biopsy from the lesion showed sheets of malignant cells with melanin deposits
(arrows) (Fig. 2B) suggestive of malignant melanoma. CT scan of chest revealed bilateral lung metastasis.
Patient was referred to oncology care in view of advanced stage. Melanoma has been
reported to metastasize to the gastrointestinal tract and bears poor prognosis [
Fig. 2(A) Endoscopy showing multiple black colored ulcero-nodular lesions in the stomach
(arrows), (B) Biopsy showing sheets of malignant cells with melanin deposits (arrows).