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T-45| Volume 52, SUPPLEMENT 1, e42, February 2020

Selective LXR α intestinal activation reduces hepatic inflammation and fibrosis during the development of chronic liver injury

DOI:https://doi.org/10.1016/j.dld.2019.12.137
Selective LXR α intestinal activation reduces hepatic inflammation and fibrosis during the development of chronic liver injury
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      Introduction: Liver fibrosis is the result of the wound healing response during chronic liver injury. Liver X receptors (LXRs) exert anti-inflammatory effects, but their activation is associated with hypertriglyceridemia and liver steatosis, due to hepatic fatty acid synthesis.
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      DOI: https://doi.org/10.1016/j.dld.2019.12.137

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      © 2019 Published by Elsevier Inc.

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