T-45| Volume 52, SUPPLEMENT 1, e42, February 2020

Selective LXR α intestinal activation reduces hepatic inflammation and fibrosis during the development of chronic liver injury

      Introduction: Liver fibrosis is the result of the wound healing response during chronic liver injury. Liver X receptors (LXRs) exert anti-inflammatory effects, but their activation is associated with hypertriglyceridemia and liver steatosis, due to hepatic fatty acid synthesis.
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