Abstract
Background
We aimed to develop a combination screening strategy for advanced colorectal neoplasia
based on the Asia-Pacific Colorectal Screening score and fecal immunochemical test
results.
Methods
We reviewed the records of participants who had undergone a colonoscopy and fecal
immunochemical test as part of a comprehensive health screening program. The prevalence
of advanced colorectal neoplasia in participants 40–49 years old was analyzed according
to Asia-Pacific Colorectal Screening scores and fecal immunochemical test results.
Results
We analyzed the data of 9205 participants 40–49 years old and 3215 participants ≥50
years old. The prevalence of advanced colorectal neoplasia in participants 40–49 years
old was 1.0%, 2.1%, 7.1%, and 13.4% in the “fecal immunochemical test (−) & Asia-Pacific
Colorectal Screening < 2,” “fecal immunochemical test (−) & Asia-Pacific Colorectal Screening ≥ 2,” “fecal immunochemical test (+) & Asia-Pacific Colorectal Screening < 2,” and “fecal immunochemical test (+) & Asia-Pacific Colorectal Screening ≥ 2” subgroups, respectively. The prevalence of advanced colorectal neoplasia in “fecal
immunochemical test (+) & Asia-Pacific Colorectal Screening ≥ 2” subgroup was higher than in participants ≥50 years old with Asia-Pacific Colorectal
Screening ≥ 4 (13.4% vs. 5.8%, P< 0.001).
Conclusions
Fecal immunochemical test-positive individuals 40–49 years old with an Asia-Pacific
Colorectal Screening ≥ 2 have a higher risk of advanced colorectal neoplasia than individuals ≥50 years old
with an Asia-Pacific Colorectal Screening ≥ 4.
Keywords
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Article info
Publication history
Published online: November 15, 2017
Accepted:
November 2,
2017
Received:
September 22,
2017
Identification
Copyright
© 2017 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
