Abstract
Crohn’s disease (CD) is a chronic inflammatory condition of the bowel, characterized
by an alternation of remission and relapse phases, leading to a progressive intestinal
damage with loss of function. Magnetic resonance enterography has been widely used
in the past for the evaluation of fistulizing disease, but its use increased over
time, being considered helpful in different moments of disease course. Intravenous
injection of Gadolinium-based contrast agents has been demonstrated to be crucial
to assess mucosal inflammation, transmural involvement, and extraintestinal disease.
Recently, Gadolinium accumulation in human tissues has been increasingly reported,
although clinical implications of this event are still unclear. In the present paper,
we review the main evidence on the topic, focusing on the potential implications for
gastroenterological practice.
Keywords
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Article info
Publication history
Published online: April 26, 2017
Accepted:
April 18,
2017
Received:
April 13,
2017
Identification
Copyright
© 2017 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
