Abstract
Background
Cholecystectomy remains the gold standard treatment of cholecystitis. Endoscopic treatment
of cholecystitis includes transpapillary gallbladder drainage. Recently, endoscopic
ultrasound-guided transmural drainage of the gallbladder (EUS-GBD) has been reported.
This study reports the cumulative experience of an international group performing
EUS-GBD.
Methods
Cases of EUS-GBD from January 2012 to November 2013 from 3 tertiary-care institutions
were captured in a registry. Patient demographics, disease characteristics, procedural
and clinical outcomes were recorded.
Results
35 patients (15 malignant, 20 benign) were included. Median age was 81 years (SD = 13.76 years), sixteen (46%) were males. Median follow-up was 91.5 days (SD = 157 days). Transmural access was obtained from the stomach (n = 17) or duodenum (n = 18). Stents placed included plastic (n = 6), metal (n = 20), or combination (n = 7). Technical success was achieved in 91.4% (n = 32). Immediate adverse events (14%) included: bleeding, stent migration, cholecystitis
and hemoperitoneum. Delayed adverse events (11%) included abscess formation and recurrence
of cholecystitis. Long-term clinical success rate was 89%. Stent type and puncture
site were not associated with immediate (p = 0.88, p = 0.62), or long-term (p = 0.47, p = 0.27) success.
Conclusions
EUS-GBD appears to be feasible, safe, and effective. Prospective studies are needed
to confirm these findings and identify the best technique to use.
Clinical trial registration
NCT01522573.
Keywords
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Article info
Publication history
Published online: June 19, 2016
Accepted:
May 23,
2016
Received:
February 2,
2016
Footnotes
☆This work was accepted and presented as a scientific presentation at Digestive Disease Week – Chicago in May 2014.
Identification
Copyright
© 2016 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
