Abstract
Background
Narrow band imaging (NBI) is used in the detection of intestinal metaplasia (IM) and
dysplasia in patients with Barrett's oesophagus (BE).
Aims
The study compared the usefulness of NBI with white-light standard endoscopy (WLSE)
for the detection of dysplasia and IM in BE and determined the prediction of the histological
diagnosis according to the mucosal and vascular patterns obtained by NBI.
Patients and methods
A total of 84 patients were prospectively enrolled in the study. Every patient underwent
a WLSE with random biopsies and after 4–6 weeks, a NBI examination was performed.
Results
NBI detected significant more IM positive biopsies than WLSE (74.5% vs. 35.9%; p < 0.0001) and significant more patients with low grade dysplasia (LGD) (7.1% vs. 0%;
p = 0.03). Taking biopsy samples from the villous pattern determined the diagnosis of
IM (80%) and biopsies from the area covered by the irregular pattern lead to the identification
of LGD in 45.4% of the cases and indefinite dysplasia (ID) in 18.2% of the cases.
Conclusion
A thorough analysis of NBI patterns may lead to real-time IM diagnosis in the absence
of the histological examination and may require targeted biopsies from the areas with
an irregular pattern for diagnosing dysplasia.
Keywords
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Article info
Publication history
Published online: May 27, 2016
Accepted:
April 20,
2016
Received:
January 25,
2016
Footnotes
☆Disclaimers: This article was prepared or completed by the authors within their personal capacities. The opinions expressed in this article are the authors’ own and do not reflect the view of the National Institutes of Health.
Identification
Copyright
© 2016 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
