A previously healthy 42-year-old man presented with a 3-month history of non-specific
abdominal pain associated with anorexia, nausea and vomiting. Apart from slightly
elevated liver enzymes, his laboratory investigations were unremarkable. An abdominal
ultrasound showed multiple liver lesions consistent with metastases; a computed tomography
scan of his chest, abdomen and pelvis confirmed these findings, however no primary
lesion was identified. At upper gastrointestinal endoscopy, multiple dark brown macules
(2–5 mm in diameter) were seen within the stomach (Fig. 1A ) and duodenum (Fig. 1B). Histological examination of biopsies of these lesions with immunostaining with
Melan-A showed features of metastatic malignant melanoma (Fig. 1C). On thorough examination of the skin, no primary lesion was identified.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Digestive and Liver DiseaseAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Reference
- Diffuse gastroduodenal metastasis of conjunctival malignant melanoma.American Journal of Gastroenterology. 2008; 103: 1321-1323
Article info
Publication history
Published online: August 14, 2014
Identification
Copyright
© 2014 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Inc. All rights reserved.
