Advertisement
Alimentary Tract| Volume 39, ISSUE 6, P524-529, June 2007

Use of alternative and complementary therapies by inflammatory bowel disease patients in an Italian tertiary referral centre

      Abstract

      Background

      Alternative and complementary therapies are increasingly used by patients with inflammatory bowel disease, but no data are available on their use in Italy.

      Aim

      To ascertain the prevalence and pattern of the use of alternative and complementary therapies, and demographic and clinical factors associated with their use in a large sample of Italian inflammatory bowel disease patients.

      Methods

      A structured questionnaire was administered to a cohort of outpatients at a tertiary referral centre.

      Results

      Five hundred and fifty-two patients completed the questionnaire; 156 (28%) reported using alternative and complementary therapies, which mainly involved homeopathy (43.6%), followed by controlled diets or dietary supplements (35.5%), herbs (28.2%), exercise (25.6%) and prayer (14.7%). Alternative and complementary therapies were used to ameliorate intestinal symptoms (52.5%), in the hope of being cured (41%) and to reduce the intake of drugs (39.7%). An improvement in well-being (45.5%) and inflammatory bowel disease symptoms (40.3%) were the most commonly reported benefits. A higher education (p = 0.027), a more frequently relapsing disease (p = 0.001) and dissatisfaction with the doctor's communication (p = 0.001) correlated with alternative and complementary therapy use. Non-compliance with conventional drugs, disease severity and curiosity regarding novel therapies were predictors of alternative and complementary therapy use.

      Conclusions

      Alternative and complementary therapies are frequently used by Italian inflammatory bowel disease patients. Doctors should improve their empathy and their understanding about possible benefits of alternative and complementary therapies.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Digestive and Liver Disease
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Eisenberg D.M.
        • Davis R.B.
        • Ettner S.L.
        • Appel S.
        • Wilkey S.
        • Van Rompay M.I.
        • et al.
        Trends in alternative medicine use in the United States, 1990–1997: results of a follow-up national survey.
        J Am Med Assoc. 1998; 280: 1569-1575
        • Molassiotis A.
        • Fernandez-Ortega P.
        • Pud D.
        • Ozden G.
        • Scott J.A.
        • Panteli V.
        • et al.
        Use of complementary and alternative medicine in cancer patients: a European survey.
        Ann Oncol. 2005; 16: 655-663
        • Ng T.P.
        • Wong M.L.
        • Hong C.Y.
        • Koh K.T.
        • Goh L.G.
        The use of complementary and alternative medicine by asthma patients.
        Q J Med. 2003; 96: 747-754
        • Fautrel B.
        • Adam V.
        • St-Pierre Y.
        • Joseph L.
        • Clarke A.E.
        • Penrod J.R.
        Use of complementary and alternative therapies by patients self-reporting arthritis or rheumatism: results from a nationwide Canadian survey.
        J Rheumatol. 2002; 29: 2435-2441
        • Astin J.A.
        Why patients use alternative medicine: results of a national study.
        J Am Med Assoc. 1998; 279: 1548-1553
        • MacLennan A.H.
        • Wilson D.H.
        • Taylor A.W.
        Prevalence and cost of alternative medicine in Australia.
        Lancet. 1996; 347: 569-573
        • Hanssen B.
        • Grimsgaard S.
        • Lauso L.
        • Fonnebo V.
        • Falkenberg T.
        • Rasmussen N.K.
        Use of complementary and alternative medicine in the Scandinavian countries.
        Scand J Prim Health Care. 2005; 23: 57-62
        • Menniti-Ippolito F.
        • Gargiulo L.
        • Bologna E.
        • Forcella E.
        • Raschetti R.
        Use of unconventional medicine in Italy: a nation-wide survey.
        Eur J Clin Pharmacol. 2002; 58: 61-64
        • Menniti-Ippolito F.
        • Bologna E.
        • Gargiulo L.
        • Forcella E.
        • Sabbadini L.L.
        • Raschetti R.
        Caratteristiche individuali e familiari degli utilizzatori di terapie non convenzionali in Italia.
        Ann Ist Super Sanità. 2004; 40: 455-461
        • Rawstone P.
        • Shanahan F.S.
        • Cronin N.C.
        • Anton P.A.
        • Löfberg R.
        • Bohman L.
        • et al.
        An international survey of the use and attitudes regarding alternative medicine by patients with inflammatory bowel disease.
        Am J Gastroenterol. 1999; 94: 1298-1303
        • Moser G.
        • Tillinger W.
        • Sachs G.
        • Maier-Dobersberger T.
        • Wyatt J.
        • Vogelsang H.
        • et al.
        Relationship between the use of unconventional therapies and disease-related concerns: a study of patients with inflammatory bowel disease.
        J Psychosom Res. 1996; 40: 503-509
        • Langhorst J.
        • Anthonisen I.B.
        • Steder-Neukamm U.
        • Ludtke R.
        • Spahn G.
        • Michalsen A.
        • et al.
        Amount of systemic steroid medication is a strong predictor for the use of complementary and alternative medicine in patients with inflammatory bowel disease: results from a German national survey.
        Inflamm Bowel Dis. 2005; 11: 287-295
        • Bensoussan M.
        • Jovenin N.
        • Garcia B.
        • Vandromme L.
        • Jolly D.
        • Bouchè O.
        • et al.
        Complementary and alternative medicine use by patients with inflammatory bowel disease.
        Gastroenterol Clin Biol. 2006; 30: 14-23
        • Langmead L.
        • Chitnis M.
        • Rampton D.S.
        Use of complementary therapies by patients with IBD may indicate psychosocial distress.
        Inflamm Bowel Dis. 2002; 8: 174-179
        • Quattropani C.
        • Ausfeld B.
        • Straumann A.
        • Heer P.
        • Seibold F.
        Complementary alternative medicine in patients with inflammatory bowel disease: use and attitudes.
        Scand J Gastroenterol. 2003; 3: 277-282
        • Hilsden R.J.
        • Verhoef M.J.
        • Best A.
        • Pocobelli G.
        Complementary and alternative medicine use by Canadian patients with inflammatory bowel disease: results from a national survey.
        Am J Gastroenterol. 2003; 98: 1563-1568
        • Markowitz J.E.
        • Mamula P.
        • delRosario J.F.
        • Baldassano R.N.
        • Lewis J.D.
        • Jawad A.F.
        • et al.
        Patterns of complementary and alternative medicine use in a population of pediatric patients with inflammatory bowel disease.
        Inflamm Bowel Dis. 2004; 10: 599-605
        • Kong S.C.
        • Hurlstone D.P.
        • Pocock C.Y.
        • Walkington L.A.
        • Farquharson N.R.
        • Bramble M.G.
        • et al.
        The incidence of self-prescribed oral complementary and alternative medicine use by patients with gastrointestinal diseases.
        J Clin Gastroenterol. 2005; 39: 138-141
        • Kane S.V.
        Systematic review: adherence issues in the treatment of ulcerative colitis.
        Aliment Pharmacol Ther. 2006; 23: 577-585
        • Hanai H.
        • Kanauchi O.
        • Mitsuyama K.
        • Andoh A.
        • Takeuchi K.
        • Takayuki I.
        • et al.
        Germinated barley foodstuff prolongs remission in patients with ulcerative colitis.
        Int J Mol Med. 2004; 13: 643-647
        • Belluzzi A.
        N-3 fatty acids for the treatment of inflammatory bowel diseases.
        Proc Nutr Soc. 2002; 61: 391-395
        • Galvez J.
        • Rodriguez-Cabezas M.E.
        • Zarzuelo A.
        Effects of dietary fiber on inflammatory bowel disease.
        Mol Nutr Food Res. 2005; 49: 601-608
        • Shanahan F.
        Probiotics in inflammatory bowel disease – therapeutic rationale and role.
        Adv Drug Deliv Rev. 2004; 56: 809-818
        • Burgmann T.
        • Rawsthorne P.
        • Bernstein N.
        Predictors of alternative and complementary medicine use in inflammatory bowel disease: do measures of conventional health care utilization relate to use?.
        Am J Gastroenterol. 2004; 99: 889-893
        • Shang A.
        • Huwiler-Muntener K.
        • Nartey L.
        • Juni P.
        • Dorig S.
        • Sterne J.
        • et al.
        Are the clinical effects of homeopathy placebo effects? Comparative study of placebo-controlled trials of homeopathy and allopathy.
        Lancet. 2005; 366: 726-732
        • D’Incà R.
        • Varnier M.
        • Mestriner C.
        • Martines D.
        • D’Odorico A.
        • Sturniolo G.C.
        Effect of moderate exercise on Crohn's disease patients in remission.
        Ital J Gastroenterol Hepatol. 1999; 31: 205-210
        • Loudon C.P.
        • Corroll V.
        • Butcher J.
        • Rawsthorne P.
        • Bernstein C.
        The effects of physical exercise on patients with Crohn's disease.
        Am J Gastroenterol. 1999; 94: 697-703
        • Langmead L.
        • Rampton D.S.
        Review article: complementary and alternative therapies for inflammatory bowel disease.
        Aliment Pharmacol Ther. 2006; 23: 341-349
        • Hilsden R.J.
        • Scott C.M.
        • Verhoef M.J.
        Complementary medicine use by patients with inflammatory bowel disease.
        Am J Gastroenterol. 1998; 93: 697-701
        • Scott C.M.
        • Verhoef M.J.
        • Hilsden R.J.
        Inflammatory bowel disease patients’ decisions to use complementary therapies: links to existing models of care.
        Compl Ther Med. 2003; 11: 22-27
        • Martin A.
        • Leone L.
        • Castagliuolo I.
        • Di Mario F.
        • Naccarato R.
        What do patients want to know about their inflammatory bowel disease?.
        Ital J Gastroenterol. 1992; 24: 477-480