Digestive and Liver Disease
Volume 42, Issue 9 , Pages 662-663 , September 2010

Cooperative genotyping for Helicobacter pylori virulence determinants strengthens the predictive value of gastric cancer risk assessment

  • Masoumeh Douraghi

      Affiliations

    • Helicobacter pylori Research Group, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
    • Department of Bacteriology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • ,
  • Yeganeh Talebkhan

      Affiliations

    • Helicobacter pylori Research Group, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
  • ,
  • Hojjat Zeraati

      Affiliations

    • Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • ,
  • Marjan Mohammadi

      Affiliations

    • Helicobacter pylori Research Group, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
    • Corresponding Author InformationCorresponding author at: Biotechnology Research Center, Pasteur Institute of Iran, Tehran 13164, Iran. Tel.: +98 2166480780; fax: +98 2166480780.

References 

  1. Amieva MR, El-Omar EM. Host–bacterial interactions in Helicobacter pylori infection. Gastroenterology. 2008;134:306–323
  2. Naito M, Yamazaki T, Tsutsumi R, et al. Influence of EPIYA-repeat polymorphism on the phosphorylation-dependent biological activity of Helicobacter pylori CagA. Gastroenterology. 2006;130:1181–1190
  3. Rhead JL, Letley DP, Mohammadi M, et al. A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer. Gastroenterology. 2007;133:926–936
  4. Sugimoto M, Zali MR, Yamaoka Y. The association of vacA genotypes and Helicobacter pylori-related gastroduodenal diseases in the Middle East. Eur J Clin Microbiol Infect Dis. 2009;28(10):1227–1236
  5. Zambon CF, Navaglia F, Basso D, et al. Helicobacter pylori babA2, cagA, and s1 vacA genes work synergistically in causing intestinal metaplasia. J Clin Pathol. 2003;56:287–291

PII: S1590-8658(10)00014-9

doi: 10.1016/j.dld.2010.01.010

Digestive and Liver Disease
Volume 42, Issue 9 , Pages 662-663 , September 2010