Digestive and Liver Disease
Volume 42, Issue 5 , Pages 359-364 , May 2010

Gastro-protective strategies in primary care in Italy: The “Gas.Pro.” survey

  • Maria A. Bianco

      Affiliations

    • U.O.C. di Gastroenterologia – Ospedale Maresca, Torre del Greco, Viale degli Aranci 2, 80131 Naples, Italy
    • Corresponding Author InformationCorresponding author. Tel.: +39 081 8490109; fax: +39 081 8490109.
  • ,
  • Gianluca Rotondano

      Affiliations

    • U.O.C. di Gastroenterologia – Ospedale Maresca, Torre del Greco, Viale degli Aranci 2, 80131 Naples, Italy
  • ,
  • Luigi Buri

      Affiliations

    • SC Gastroenterologia – Ospedale di Cattinara, Trieste, Italy
  • ,
  • Francesco Tessari

      Affiliations

    • CED-IDEA 99 srl-Padova, Italy
  • ,
  • Livio Cipolletta

      Affiliations

    • U.O.C. di Gastroenterologia – Ospedale Maresca, Torre del Greco, Viale degli Aranci 2, 80131 Naples, Italy
  • ,
  • for the Gas.Pro. Italian Group

Received 29 May 2009 ,Accepted 15 November 2009.

References 

  1. Lazzaroni M, Bianchi Porro G. Prophylaxis and treatment of non-steroidal anti-inflammatory drug-induced upper gastrointestinal side-effects. Dig Liver Dis. 2001;33(Suppl. 2):S44–58
  2. García Rodríguez LA, Barreales Tolosa L. Risk of upper gastrointestinal complications among users of traditional NSAIDs and COXIBs in the general population. Gastroenterology. 2007;132:498–506
  3. Lazzaroni M, Porro GB. Management of NSAID-induced gastrointestinal toxicity: focus on proton pump inhibitors. Drugs. 2009;69:51–69
  4. Targownik LE, Bolton JM, Metge CJ, et al. Selective serotonin reuptake inhibitors are associated with a modest increase in the risk of upper gastrointestinal bleeding. Am J Gastroenterol. 2009;104:1475–1482
  5. Lazzaroni M, Battocchia A, Bianchi Porro G. COXIBs and non-selective NSAIDs in the gastroenterological setting: what should patients and physicians do?. Dig Liver Dis. 2007;39:589–596
  6. Targownik LE, Metge CJ, Leung S. Underutilization of gastroprotective strategies in aspirin users at increased risk of upper gastrointestinal complications. Aliment Pharmacol Ther. 2008;28:88–96
  7. American Gastroenterological Association , Wilcox CM, Allison J, et al. Consensus development conference on the use of nonsteroidal anti-inflammatory agents, including cyclooxygenase-2 enzyme inhibitors and aspirin. Clin Gastroenterol Hepatol. 2006;4:1082–1089
  8. Chan FK, Abraham NS, Scheiman JM, et al. Management of patients on nonsteroidal anti-inflammatory drugs: a clinical practice recommendation from the first international working party on gastrointestinal and cardiovascular effects of nonsteroidal anti-inflammatory drugs and anti-platelet agents. Am J Gastroenterol. 2008;103:2908–2918
  9. Bhatt DL, Scheiman J, Abraham NS. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. Am J Gastroenterol. 2008;103:2890–2907
  10. Lanza FL, Chan FK, Quigley EM. Practice Parameters Committee of the American College of Gastroenterology. Guidelines for prevention of NSAID-related ulcer complications. Am J Gastroenterol. 2009;104:728–738
  11. Rostom A, Moayyedi P, Hunt R. Canadian consensus guidelines on long-term nonsteroidal anti-inflammatory drug therapy and the need for gastroprotection: benefits versus risks. Aliment Pharmacol Ther. 2009;29:481–496
  12. Elnachef N, Scheiman JM, Fendrick AM, et al. Changing perceptions and practices regarding aspirin, nonsteroidal anti-inflammatory drugs, and cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs among US primary care providers. Aliment Pharmacol Ther. 2008;28:1249–1258
  13. Johnell K, Fastbom J. Concomitant use of gastroprotectiove drugs among elderly NSAID/COX-2 selective inhibitor users: a nationwide register-based study. Clin Drug Investig. 2008;28:687–695
  14. Abraham NS, El-Serag HB, Johnson ML, et al. National adherence to evidence-based guidelines for the prescription of nonsteroidal anti-inflammatory drugs. Gastroenterology. 2005;129:1171–1178
  15. Goldstein JL, Howard KB, Walton SM, et al. Impact of adherence to concomitant gastroprotective therapy on nonsteroidal-related gastroduodenal ulcer complications. Clin Gastroenterol Hepatol. 2006;4:1337–1345
  16. Van der Linden MW, Gaugris S, Kuipers EJ, et al. Gastroprotection among new chronic users of non-steroidal anti-inflammatory drugs: a study of utilization and adherence in The Netherlands. Curr Med Res Opin. 2009;25:195–204
  17. Lanas A. Prevention of aspirin-induced gastroduodenal damage: H. pylori infection eradication versus proton pump inhibitors or both. Dig Liver Dis. 2004;36:655–657
  18. Ray WA, Chung CP, Stein CM, et al. Risk of peptic ulcer hospitalizations in users of NSAIDs with gastroprotective cotherapy versus coxibs. Gastroenterology. 2007;133:790–798
  19. Abraham NS, Castillo DL, Hartman C. National mortality following upper gastrointestinal or cardiovascular events in older veterans with recent nonsteroidal anti-inflammatory drug use. Aliment Pharmacol Ther. 2008;28:97–106
  20. Targownik LE, Metge CJ, Leung S, et al. The relative efficacies of gastroprotective strategies in chronic users of nonsteroidal anti-inflammatory drugs. Gastroenterology. 2008;134:937–944
  21. Bianchi Porro G, Lazzaroni M, Imbesi V, et al. Efficacy of pantoprazole in the prevention of peptic ulcers, induced by non-steroidal anti-inflammatory drugs: a prospective, placebo-controlled, double-blind, parallel-group study. Dig Liver Dis. 2000;32:201–208
  22. Juurlink DN, Gomes T, Ko DT, et al. A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ. 2009;180:713–718
  23. Siller-Matula JM, Spiel AO, Lang IM, et al. Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel. Am Heart J. 2009;157:148.e1–5

PII: S1590-8658(09)00438-1

doi: 10.1016/j.dld.2009.11.003

Digestive and Liver Disease
Volume 42, Issue 5 , Pages 359-364 , May 2010